MedE 99. Undergraduate Research in Medical Engineering. Variable units as arranged with the advising faculty member; first, second, third terms. Undergraduate research with a written report at the end of each term; supervised by a Caltech faculty member, or co-advised by a Caltech faculty member and an external researcher. Graded pass/fail. Instructor: Staff.
MedE 100 abc. Medical Engineering Seminar. 1 unit; first, second, third terms. All PhD degree candidates in Medical Engineering are required to attend all MedE seminars. If there is no MedE seminar during a week, then the students should go to any other graduate-level seminar that week. Students should broaden their knowledge of the engineering principles and sciences of medical engineering. Students are expected to learn the forefronts of the research and development of medical materials, technologies, devices and systems from the seminars. Graded pass/fail. Instructors: Gao, Tai and Wang.
MedE 101. Introduction to Clinical Physiology and Pathophysiology for Engineers. 9 units (3-0-6); First term. Prerequisites: No Prerequisites, Bi 1 or equivalent recommended. The goal of this course is to introduce engineering scientists to medical physiological systems: with a special emphasis on the clinical relevance. The design of the course is to present two related lectures each week: An overview of the physiology of a system followed by examples of current clinical medical challenges and research highlighting diagnostic and therapeutic modalities. The final three weeks of the course will be a mini-work shop where the class explores challenging problems in medical physiology. The course ultimately seeks to promote a bridge between relevant clinical problems and engineering scientists who desire to solve them. Graded pass/fail. Instructor: Petrasek.
E/ME/MedE 105 ab. Design for Freedom from Disability. 9 units (3-0-6). For course description, see Engineering.
ChE/BE/MedE 112. Design, Invention, and Fundamentals of Microfluidic Systems. 9 units (3-0-6). For course description, see Chemical Engineering.
EE/MedE 114ab. Analog Circuits Design. 12 units (4-0-8). For course description, see Electrical Engineering.
EE/MedE 115. Micro-/Nano-scales Electro-optics. 9 units (3-0-6). For course description, see Electrical Engineering.
MS/ME/MedE 116. Mechanical Behavior of Materials. 9 units (3-0-6). For course description, see Materials Science.
EE/MedE 124. Mixed-mode Integrated Circuits. 9 units (3-0-6). For course description, see Electrical Engineering.
EE/CS/MedE 125. Digital Electronics and Design with FPGAs and VHDL. 9 units (3-6-0). For course description, see Electrical Engineering.
MedE/EE/BE 168 abc. Biomedical Optics: Principles and Imaging. 9 units (4-0-5) each; parts a and b are taught in second and third terms in odd academic years starting 2019–20 and part c is taught in second term in even academic years starting 2020-21. Prerequisites: instructor’s permission. Part a covers the principles of optical photon transport in biological tissue. Topics include a brief introduction to biomedical optics, single-scatterer theories, Monte Carlo modeling of photon transport, convolution for broad-beam responses, radiative transfer equation and diffusion theory, hybrid Monte Carlo method and diffusion theory, and sensing of optical properties and spectroscopy, (absorption, elastic scattering, Raman scattering, and fluorescence). Part b covers established optical imaging technologies. Topics include ballistic imaging (confocal microscopy, two-photon microscopy, super-resolution microscopy, etc.), optical coherence tomography, Mueller optical coherence tomography, and diffuse optical tomography. Part c covers emerging optical imaging technologies. Topics include photoacoustic tomography, ultrasound-modulated optical tomography, optical time reversal (wavefront shaping/engineering), and ultrafast imaging. Instructor: Wang.
EE/CS/MedE 175. Digital Circuits Analysis and Design with Complete VHDL and RTL Approach. 9 units (3-6-0). For course description, see Electrical Engineering.
EE/BE/MedE 185. MEMS Technology and Devices. 9 units (3-0-6). For course description, see Electrical Engineering.
EE/MedE 187. VLSI and ULSI Technology. 9 units (3-0-6). For course description, see Electrical Engineering.
ChE/BE/MedE 188. Molecular Imaging. 9 units (3-0-6). For course description, see Chemical Engineering.
BE/EE/MedE 189 ab. Design and Construction of Biodevices. 189 a, 12 units (3-6-3) offered both first and third terms. 189b, 9 units (0-9-0) offered only third term. For course description, see Bioengineering.
MedE 199. Special Topics in Medical Engineering. Units to be arranged, terms to be arranged. Subject matter will change from term to term depending upon staff and student interest, but will generally center on the understanding and applying engineering for medical problems. Instructor: Staff.
MedE 201ab. Principles and Design of Medical Devices. 9 units (3-0-6); second and third term. Prerequisite: instructor’s permission. This course provides a broad coverage on the frontiers of medical diagnostic and therapeutic technologies and devices based on multidisciplinary engineering principles. Topics include biomaterials and biomechanics; micro/nanofluidics; micro/nano biophotonics and medical imaging; medical electronics, wireless communications through the skin and tissue; electrograms and biotic/abiotic interface; biochips, microPCR and sequencer and biosensors; micro/nano implants. The course will focus on the scientific fundamentals specific to medical applications. However, both the lectures and assignments will also emphasize the design aspects of the topics as well as up-to-date literature study. Instructors: Tai and Gao.
MedE 202. Sensors in Medicine. 9 units (3-0-6); second term. Prerequisites: None. Sensors play a very important role in all aspect of modern life. This course is an essential introduction to a variety of physical, chemical and biological sensors that are used in medicine and healthcare. The fundamental recognition mechanisms, transduction principles and materials considerations for designing powerful sensing and biosensing devices will be covered. We will also discuss the development of emerging electronic-skin, wearable and soft electronics toward personalized health monitoring. Participants in the course will develop proposals for novel sensing technologies to address the current medical needs. Instructor: Gao.
MedE 205. New Frontiers in Medical Technologies. 6 units (2-0-4); third term. Prerequisites: None but knowledge of semiconductor physics and some system engineering, basic electrical engineering highly recommended. New Frontiers of Medical Technologies is an introductory graduate level course that describes space technologies, instruments, and engineering techniques with current and potential applications in medicine. These technologies have been originally and mainly developed for space exploration. Spinoff applications to medicine have been explored and proven with various degrees of success and maturity. This class introduces these topics, the basics of the technologies, their intended original space applications, and the medical applications. Topics include but are not limited to multimodal imaging, UV/Visible/NIR imaging, imaging spectrometry, sensors, robotics, and navigation. Graded pass/fail. Instructor: Nikzad.
MedE/BE/Ae 243. Physiological Mechanics. 9 units (3-0-6); second term. Prerequisites: Ae/APh/CE/ME 101 abc or equivalent or ChE 103 a. Internal flows: steady and pulsatile blood flow in compliant vessels, internal flows in organisms. Fluid dynamics of the human circulatory system: heart, veins, and arteries (microcirculation). Mass and momentum transport across membranes and endothelial layers. Fluid mechanics of the respiratory system. Renal circulation and circulatory system. Biological pumps. Low and High Reynolds number locomotion. Instructor: TBD/
MedE 291. Research in Medical Engineering. Units to be arranged, first, second, third terms. Qualified graduate students are advised in medical engineering research, with the arrangement of MedE staff.