Ch 1 ab
General Chemistry
6 units (3-0-3) first term
|
9 units (4-0-5) second term
Lectures and recitations dealing with the principles of chemistry. First term: electronic structure of atoms, periodic properties, ionic substances, covalent bonding, Lewis representations of molecules and ions, shapes of molecules, Lewis acids and bases, Bronsted acids and bases, hybridization and resonance, bonding in solids. Second term: chemical equilibria, oxidation and reduction, thermodynamics, kinetics, introduction to organic chemistry and the chemistry of life. Graded pass/fail.
Instructors:
Lewis, Rees, Blake
Ch/APh 2
Introduction to Energy Sciences
9 units (4-0-5)
|
third term
Prerequisites: Ch 1 ab, Ph 1 ab, Ma 1 ab.
Energy production and transduction in biological, chemical, and nuclear reactions. Bioenergetics: energy sources and storage; components of biological energy flows: pumps, motors, and solar cells; circuitry of biological energy flows and biological energy transduction pathways. Chemistry of energy production and utilization: fossil fuel utilization and energy conversion pathways; artificial photosynthesis, solar cells, and solar energy conversion. Principles of nuclear energy production: nuclear energy decay processes, fission and fusion reactions, and reactor principles. Not offered on a pass/fail basis. Satisfies the menu requirement of the Caltech core curriculum. Not offered 2011-12.
Ch 3 a
Fundamental Techniques of Experimental Chemistry
6 units (1-3-2)
|
first, second, third terms
Introduces the basic principles and techniques of synthesis and analysis and develops the laboratory skills and precision that are fundamental to experimental chemistry. Freshmen who have gained advanced placement into Ch 41 or Ch 21, or who are enrolled in Ch 10, are encouraged to take Ch 3 a in the fall term. Graded pass/fail.
Instructor:
Mendez
Ch 3 x
Experimental Methods in Solar Energy Conversion
6 units (1-3-2)
|
first, second, third terms
Introduces concepts and laboratory methods in chemistry and materials science centered on the theme of solar energy conversion and storage. Students will perform experiments involving optical spectroscopy, electrochemistry, laser spectroscopy, nanoparticle synthesis, photochemistry, and photoelectrochemistry, culminating in the construction and testing of dye-sensitized solar cells. A lecture component is included.
Instructor:
Mendez
Ch 4 ab
Synthesis and Analysis of Organic and Inorganic Compounds
9 units (1-6-2)
Prerequisites: Ch 1 (or the equivalent) and Ch 3 a or Ch 3 x.
Previous or concurrent enrollment in Ch 41 is strongly recommended. Introduction to methods of synthesis, separation, purification, and characterization used routinely in chemical research laboratories. Ch 4 a emphasizes spectroscopic methods of analysis; Ch 4 b stresses applications of chromatography in addition to more classical separation techniques. Ch 4 a, second term; Ch 4 b, third term only.
Instructor:
Mendez
Ch 5 ab
Advanced Techniques of Synthesis and Analysis
Ch 5 a 12 units (1-9-2), second term
|
Ch 5 b 9 units (1-6-2), first term
Prerequisites: Ch 4 ab. Ch 102 strongly recommended for Ch 5 b.
Modern synthetic chemistry. Specific experiments may change from year to year. Experiments illustrating the multistep syntheses of natural products (Ch 5 a), coordination complexes, and organometallic complexes (Ch 5 b) will be included. Methodology will include advanced techniques of synthesis and instrumental characterization. Terms may be taken independently.
Instructors:
Grubbs (a), Agapie (b)
Ch 6 ab
Physical and Biophysical Chemistry Laboratory
10 units (1-6-3)
|
second, third terms
Prerequisites: Ch 1, Ch 4 ab, and Ch 21 or Ch 24 or equivalents (may be taken concurrently).
Introduction to modern physical methods in chemistry and biology. Techniques include laser spectroscopy, microwave spectroscopy, electron spin resonance, nuclear magnetic resonance, mass spectrometry, FT-IR, fluorescence, X-ray diffraction, scanning probe microscopies, and UHV surface methods. The two terms can be taken in any order.
Instructors:
Beauchamp, Weitekamp
Ch 7
Advanced Experimental Methods in Bioorganic Chemistry
9 units (1-6-2)
|
third term
Prerequisites: Ch 41 abc, and Bi/Ch 110, Ch 4 ab. Enrollment by instructor's permission. Preference will be given to students who have taken Ch 5 a or Bi 10.
This advanced laboratory course will provide experience in the powerful contemporary methods for polypeptide and oligonucleotide synthesis. Experiments will address nucleic acid and amino acid protecting group strategies, biopolymer assembly and isolation, and product characterization. A strong emphasis will be placed on understanding the chemical basis underlying the successful utilization of these procedures. In addition, experiments to demonstrate the application of commercially available enzymes for useful synthetic organic transformations will be illustrated.
Instructor:
Hsieh-Wilson
Ch 8
Experimental Procedures of Synthetic Chemistry
9 units (1-6-2)
|
first term
Prerequisites: Ch 1 ab and Ch 3 a or Ch 3 x.
Instruction in fundamental synthesis, separation, and characterization procedures used in chemical research.
Instructor:
Mende
Ch/ChE 9
Chemical Synthesis and Characterization for Chemical Engineering
9 units (1-6-2)
|
third term
Prerequisites: Ch 1 ab and Ch 3 a or Ch 3 x.
Instruction in synthesis, separation, purification, and physical and spectroscopic characterization procedures of model organic and inorganic materials, with emphasis on chemical reactions such as polymerization, catalysis, and light absorption and emission. Enrollment priority given to chemical engineering majors.
Instructor:
Mendez
Ch 10 abc
Frontiers in Chemistry
3 units (2-0-1) first, second terms
|
8 units (1-6-1) third term
Prerequisites: Ch 10 c prerequisites are Ch 10 ab, Ch 3 a or Ch 3 x, and either Ch 1 ab, Ch 41 ab, or Ch 21 ab, and instructor's permission.
Open for credit to freshmen and sophomores. Ch 10 ab is a weekly seminar by a member of the chemistry department on a topic of current research; the topic will be presented at an informal, introductory level. The other weekly session will acquaint students with the laboratory techniques and instrumentation used on the research topics. Ch 10 c is a research-oriented laboratory course, which will be supervised by a chemistry faculty member. Weekly class meetings will provide a forum for participants to discuss their research projects. Graded pass/fail.
Instructors:
Dervan, Hoelz
Ch 14
Chemical Equilibrium and Analysis
6 units (2-0-4)
|
third term
A systematic treatment of ionic equilibria in solution. Topics covered include acid-base equilibria in aqueous and nonaqueous solutions, complex ion formation, chelation, oxidation-reduction reactions, and some aspects of reaction mechanisms.
Instructors:
Richards, Shahgholi
Ch 15
Chemical Equilibrium and Analysis Laboratory
10 units (0-6-4)
|
first term
Prerequisites: Ch 1 ab, Ch 3 a or Ch 3 x, Ch 14, or instructor's permission.
Laboratory experiments are used to illustrate modern instrumental techniques that are currently employed in industrial and academic research. Emphasis is on determinations of chemical composition, measurement of equilibrium constants, evaluation of rates of chemical reactions, and trace-metal analysis.
Instructor:
Dalleska
Ch 21 abc
Physical Chemistry
9 units (3-0-6)
|
first, second, third terms
Prerequisites: Ch 1 ab, Ph 2 ab, Ma 2 ab.
Atomic and molecular quantum mechanics, spectroscopy, thermodynamics, statistical mechanics, and chemical kinetics.
Instructors:
Okumura, Cai, Miller
Ch 24
Introduction to Biophysical Chemistry: Spectroscopy
9 units (3-0-6)
|
second term
Prerequisites: Ma 1 abc, Ph 1 abc, Ph 2 ab or Ph 12 a, and Ch 21 a or Ph 12 b.
Develops the basic principles of the interaction of light with matter, including spectroscopic and scattering methods of macromolecular structure determination, with emphasis on biochemical and biophysical applications.
Instructor:
Heath
Ch 25
Introduction to Biophysical Chemistry: Thermodynamics
9 units (3-0-6)
|
third term
Prerequisites: Ma 1 abc, Ph 1 abc and Ph 2 ab; Ch 21 a and Ch 24 recommended.
Develops the basic principles of solution thermodynamics, transport processes, and reaction kinetics, with emphasis on biochemical and biophysical applications.
Instructor:
Rees
Ch 41 abc
Organic Chemistry
9 units (3-0-6)
|
first, second, third terms
Prerequisites: Ch 1 ab or instructor's permission.
The synthesis, structures, and mechanisms of reactions of organic compounds.
Instructors:
Dougherty, Stoltz
Ch 80
Chemical Research
Units in accordance with work accomplished.
Prerequisites: consent of research supervisor.
Offered to B.S. candidates in chemistry. Experimental and theoretical research requiring a report containing an appropriate description of the research work.
Ch 81
Independent Reading in Chemistry
Units by arrangement
Prerequisites: instructor's permission.
Occasional advanced work involving reading assignments and a report on special topics. No more than 12 units in Ch 81 may be used as electives in the chemistry option.
Ch 82
Senior Thesis Research
9 units
|
first, second, third terms
Prerequisites: instructor's permission.
Three terms of Ch 82 are to be completed during the junior and/or senior year of study. At the end of the third term, a thesis of approximately 20 pages (excluding figures and references) will be presented to the mentor and the Chemistry Curriculum and Undergraduate Studies Committee. An oral thesis defense will be arranged by the CUSC. The thesis must be approved by both the research mentor and the CUSC. The first two terms of Ch 82 will be taken on a pass/fail basis, and the third term will carry a letter grade.
Instructor:
Rees
Ch 90
Oral Presentation
3 units (2-0-1)
|
second term
Training in the techniques of oral presentation of chemical and biochemical topics. Practice in the effective organization and delivery of technical reports before groups. Graded pass/fail.
Instructors:
Zewail, Bikle
Ch/ChE 91
Scientific Writing
3 units (2-0-1)
|
first, second, third term
Training in the writing of scientific research papers for chemists and chemical engineers. Fulfills the Institute scientific writing requirement.
Instructors:
Parker, Richards, Davis
Ch 102
Introduction to Inorganic Chemistry
9 units (3-0-6)
|
third term
Prerequisites: Ch 41 ab.
Structure and bonding of inorganic species with special emphasis on spectroscopy, ligand substitution processes, oxidation-reduction reactions, and biological inorganic chemistry. Letter grades only.
Instructors:
Agapie, Peters
Bi/Ch 110
Introduction to Biochemistry
12 units (4-0-8)
|
first term
Prerequisites: Ch 41 abc or instructor's permission.
Lectures and recitation introducing the molecular basis of life processes, with emphasis on the structure and function of proteins. Topics will include the derivation of protein structure from the information inherent in a genome, biological catalysis, the intermediary metabolism that provides energy to an organism, and the use of DNA manipulations, cloning, and expression of proteins in foreign hosts to study protein structure and function.
Instructors:
Richards, Biochemistry faculty
Bi/Ch 111
Biochemistry of Gene Expression
12 units (4-0-8)
|
second term
Prerequisites: Bi/Ch 110; Bi 8 and Bi 122 recommended.
Lectures and recitation on the molecular basis of biological structure and function. Emphasizes the storage, transmission, and expression of genetic information in cells. Specific topics include DNA replication, recombination, repair and mutagenesis, transcription, RNA processing, and protein synthesis.
Instructors:
Campbell, Parker
Ch 112
Inorganic Chemistry
9 units (3-0-6)
|
first term
Prerequisites: Ch 102 or instructor's permission.
Introduction to group theory, ligand field theory, and bonding in coordination complexes and organo- transition metal compounds. Systematics of synthesis, bonding, and reactivities of commonly encountered classes of transition metal compounds.
Instructor:
Bercaw
Bi/Ch 113
Biochemistry of the Cell
12 units (4-0-8)
|
third term
Prerequisites: Bi/Ch 110; Bi 9 recommended.
Lectures and recitation on the biochemistry of basic cellular processes in the cytosol and at the cell surface, with emphasis on signal transduction, membrane trafficking, and control of cell division. Specific topics include cell-cell signaling, control of gene expression by cell surface molecules, tumorigenesis, endocytosis, exocytosis, viral entry, and cell cycle regulation.
Instructor:
Chan
Ch 117
Introduction to Electrochemistry
9 units (3-0-6)
|
second term
Discussion of the structure of electrode-electrolyte interface, the mechanism by which charge is transferred across it, and experimental techniques used to study electrode reactions. Topics change from year to year but usually include diffusion currents, polarography, coulometry, irreversible electrode reactions, the electrical double layer, and kinetics of electrode processes. Not offered 2011-12.
Ch 120 ab
Nature of the Chemical Bond
9 units, part a (3-0-6), part b (1-1-7)
|
part a, second term and part b, third term
Prerequisites: general exposure to quantum mechanics (e.g., Ch 21 a).
Modern ideas of chemical bonding, with an emphasis on qualitative concepts useful for predictions of structures, energetics, excited states, and properties. Part a: The quantum mechanical basis for understanding bonding, structures, energetics, and properties of materials (polymers, ceramics, metals alloys, semiconductors, and surfaces), including transition metal and organometallic systems with a focus on chemical reactivity. The emphasis is on explaining chemical, mechanical, electrical, and thermal properties of materials in terms of atomistic concepts. Part b: The student does an individual research project using modern quantum chemistry computer programs to calculate wavefunctions, structures, and properties of real molecules.
Instructor:
Goddard
Ch 121 ab
Atomic-Level Simulations of Materials and Molecules
Ch 121 a: 9 units (3-0-6) third term
|
Ch 121 b (1-1-7) first term
Prerequisites: Ch 21 a or Ch 125 a.
Atomistic-based methods for predicting the structures and properties of molecules and solids and simulating the dynamical properties. The course will highlight theoretical foundations and applications of atomistic simulations to current problems in such areas as biological systems (proteins, DNA, carbohydrates, lipids); polymers (crystals, amorphous systems, copolymers); semiconductors (group IV, III-V, surfaces, defects); inorganic systems (ceramics, zeolites, superconductors, and metals); organometallics, and catalysis (heterogeneous and homogeneous). Part a covers the basic methods with hands-on applications to systems of interest using modern software. All homework and exams emphasize computer-based solutions. Part b: each student selects a research project and uses atomistic simulations to solve it.
Instructor:
Goddard
Ch 122
Structure Determination by X-ray Crystallography
9 units (3-0-6)
|
first term
Prerequisites: Ch 21 abc or instructor's permission.
Methods for solving the crystal structures of organic and inorganic molecules, peptides, nucleic acids, and proteins. Topics include symmetry, space groups, diffraction by crystals, the direct and reciprocal lattice, powder diffraction, Patterson and direct methods for phase determination, isomorphous replacement phasing for macromolecules, and structure refinement.
Instructor:
Day
Ch 125 abc
The Elements of Quantum Chemistry
9 units (3-0-6)
|
first, second, third terms
Prerequisites: Ch 21 abc or an equivalent brief introduction to quantum mechanics.
A first course in molecular quantum mechanics consisting of a quantitative treatment of quantum mechanics with applications to systems of interest to chemists. The basic elements of quantum mechanics, the electronic structure of atoms and molecules, the interactions of radiation fields and matter, scattering theory, and reaction rate theory.
Instructors:
McKoy (a, b), Weitekamp (c)
Ch 126
Molecular Spectra and Molecular Structure
9 units (3-0-6)
|
third term
Prerequisites: Ch 21 and Ch 125 a taken concurrently, or instructor's permission.
Quantum mechanical foundations of the spectroscopy of molecules. Topics include quantum theory of angular momentum, rovibrational Hamiltonian for polyatomic molecules, molecular symmetry and permutation-inversion groups, electronic spectroscopy, interaction of radiation and matter. Not offered 2011-12.
Ge/Ch 127
Nuclear Chemistry
9 units (3-0-6)
|
second term
Prerequisites: instructor's permission.
A survey course in the properties of nuclei, and in atomic phenomena associated with nuclear-particle detection. Topics include rates of production and decay of radioactive nuclei; interaction of radiation with matter; nuclear masses, shapes, spins, and moments; modes of radioactive decay; nuclear fission and energy generation. Given in alternate years; offered 2011-12.
Instructor:
Burnett
Ge/Ch 128
Cosmochemistry
9 units (3-0-6)
|
third term
Prerequisites: instructor's permission.
Examination of the chemistry of the interstellar medium, of protostellar nebulae, and of primitive solar-system objects with a view toward establishing the relationship of the chemical evolution of atoms in the interstellar radiation field to complex molecules and aggregates in the early solar system. Emphasis will be placed on identifying the physical conditions in various objects, timescales for physical and chemical change, chemical processes leading to change, observational constraints, and various models that attempt to describe the chemical state and history of cosmological objects in general and the early solar system in particular. Not offered 2011-12.
Instructor:
Blake
Bi/Ch 132
Biophysics of Macromolecules
9 units (3-0-6); first term
|
Recommended prerequisite: Bi/Ch 110
Structural and functional aspects of nucleic acids and proteins, including hybridization; electrophoretic behavior of nucleic acids; principles and energetics of folding of polypeptide chains in proteins; allostery and cooperativity in protein action; enzyme kinetics and mechanisms; and methods of structure determination, such as X-ray diffraction and magnetic resonance. Structure and function of metalloenzymes.
Instructors:
Beauchamp, Cai
Ch 135 ab
Chemical Dynamics
9 units (3-0-6)
|
part a, second term
Prerequisites: Ch 21 abc and Ch 41 abc, or equivalent, or instructor's permission.
Part a: introduction to the dynamics of chemical reactions. Topics include scattering cross sections, rate constants, intermolecular potentials, reactive scattering, nonadiabatic processes, statistical theories of unimolecular reactions, and the application of laser and molecular beam techniques to the study of reaction mechanisms. Part b: the quantum description of chemical reactions. The scattering matrix. The calculation of reaction cross sections, probabilities, and rate constants. Collision lifetimes and resonances. Classical trajectories. The two terms can be taken independently. Part b not offered 2011-12.
Instructors:
Marcus, Okumura
Ch/ChE 140 ab
Principles and Applications of Semiconductor Photoelectrochemistry
9 units (3-0-6)
|
second, third terms
Prerequisites: APh/EE 9 ab or instructor's permission.
The properties and photoelectrochemistry of semiconductors and semiconductor/liquid junction solar cells will be discussed. Topics include optical and electronic properties of semiconductors; electronic properties of semiconductor junctions with metals, liquids, and other semiconductors, in the dark and under illumination, with emphasis on semiconductor/liquid junctions in aqueous and nonaqueous media. Problems currently facing semiconductor/liquid junctions and practical applications of these systems will be highlighted. Not offered 2011-12.
Ch 143
NMR Spectroscopy for Structural Identification
9 units (3-0-6)
|
first term
Prerequisites: Ch 41 abc.
This course will address both one-dimensional and two-dimensional techniques in NMR spectroscopy which are essential to elucidating structures of organic and organometallic samples. Dynamic NMR phenomena, multinuclear, paramagnetic and NOE effects will also be covered. An extensive survey of multipulse NMR methods will also contribute to a clear understanding of two-dimensional experiments. (Examples for Varian NMR instrumentation will be included.)
Instructor:
Virgil
Ch 144 ab
Advanced Organic Chemistry
9 units (3-0-6)
|
first, second terms
Prerequisites: Ch 41 abc; Ch 21 abc recommended.
An advanced survey of selected topics in modern physical organic chemistry. Topics vary from year to year and may include structural and theoretical organic chemistry; molecular recognition/supramolecular chemistry; reaction mechanisms and the tools to study them; reactive intermediates; materials chemistry; pericyclic reactions; and photochemistry. Part a only offered second term.
Instructor:
TBA
Ch 145
Bioorganic Chemistry of Proteins
9 units (3-0-6)
|
first term
Prerequisites: Ch 41 abc; Bi/Ch 110 recommended.
An advanced survey of current and classic topics in bioorganic chemistry/chemical biology. The content will vary from year to year and may include the structure, function, and synthesis of peptides and proteins; enzyme catalysis and inhibition; carbohydrates and glycobiology; chemical genetics; genomics and proteomics; posttranslational modifications; chemical tools to study cellular dynamics; and enzyme evolution. Not offered 2011-12.
Ch 146
Bioorganic Chemistry of Nucleic Acids
9 units (3-0-6)
|
third term
Prerequisites: Ch 41 ab.
The course will examine the bioorganic chemistry of nucleic acids, including DNA and RNA structures, molecular recognition, and mechanistic analyses of covalent modification of nucleic acids. Topics include synthetic methods for the construction of DNA and RNA; separation techniques; recognition of duplex DNA by peptide analogs, proteins, and oligonucleotide-directed triple helical formation; RNA structure and RNA as catalysts (ribozymes). Not offered 2011-12.
Ch/ChE 147
Polymer Chemistry
9 units (3-0-6)
|
second, third term
Prerequisites: Ch 41 abc.
An introduction to the chemistry of polymers, including synthetic methods, mechanisms and kinetics of macromolecule formation, and characterization techniques.
Instructors:
Grubbs, Gilchrist
ChE/Ch 148
Polymer Physics
9 units (3-0-6)
|
third term
An introduction to the physics that govern polymer structure and dynamics in liquid and solid states, and to the physical basis of characterization methods used in polymer science. The course emphasizes the scaling aspects of the various physical properties. Topics include conformation of a single polymer chain under different solvent conditions; dilute and semi-dilute solutions; thermodynamics of polymer blends and block copolymers; rubber elasticity; polymer gels; linear viscoelasticity of polymer solutions and melts; glass transition and crystallization. Given in alternate years; not offered 2011-12.
Instructor:
Wang
Ch 153 ab
Advanced Inorganic Chemistry
9 units (3-0-6)
|
second, third terms
Prerequisites: Ch 112 and Ch 21 abc or concurrent registration.
Ch 153 a: Topics in modern inorganic chemistry. Electronic structure, spectroscopy, and photochemistry with emphasis on examples from the modern research literature. Ch 153 b: Applications of physical methods toward the characterization of inorganic and bioinorganic species. A range of spectroscopic approaches will be covered.
Instructors:
Gray, Winkler (a); Peters (b)
Ch 154 ab
Organometallic Chemistry
9 units (3-0-6)
|
second, third terms
Prerequisites: Ch 112 or equivalent.
A general discussion of the reaction mechanisms and the synthetic and catalytic uses of transition metal organometallic compounds. Second term: a survey of the elementary reactions and methods for investigating reaction mechanisms. Third term: contemporary topics in inorganic and organometallic synthesis, structure and bonding, and applications in catalysis. Part b not offered 2011-12.
Instructors:
Labinger, Bercaw
ChE/Ch 155
Chemistry of Catalysis
9 units (3-0-6)
|
third term
Discussion of homogeneous and heterogeneous catalytic reactions, with emphasis on the relationships between the two areas and their role in energy problems. Topics include catalysis by metals, metal oxides, zeolites, and soluble metal complexes; utilization of hydrocarbon resources; and catalytic applications in alternative energy approaches. Given in alternate years; not offered 2011-12.
Instructors:
Davis, Labinger
ChE/Ch 164
Introduction to Statistical Thermodynamics
9 units (3-0-6)
|
second term
Prerequisites: Ch 21 abc or instructor's permission.
An introduction to the fundamentals and simple applications of statistical thermodynamics. Foundation of statistical mechanics; partition functions for various ensembles and their connection to thermodynamics; fluctuations; noninteracting quantum and classical gases; heat capacity of solids; adsorption; phase transitions and order parameters; linear response theory; structure of classical fluids; computer simulation methods.
Instructors:
Wang, Miller
ChE/Ch 165
Chemical Thermodynamics
9 units (3-0-6)
|
first term
Prerequisites: ChE 63 ab or instructor's permission.
An advanced course emphasizing the conceptual structure of modern thermodynamics and its applications. Review of the laws of thermodynamics; thermodynamic potentials and Legendre transform; equilibrium and stability conditions; metastability and phase separation kinetics; thermodynamics of single-component fluid and binary mixtures; models for solutions; phase and chemical equilibria; surface and interface thermodynamics; electrolytes and polymeric liquids.
Instructor:
Wang
Ch 166
Nonequilibrium Statistical Mechanics
9 units (3-0-6)
|
third term
Prerequisites: Ch 21 abc or equivalent.
Transport processes in dilute gases; Boltzmann equation; Brownian motion; Langevin and Fokker-Planck equations; linear response theory; time-correlation functions and applications; nonequilibrium thermodynamics.
Instructor:
Marcus
BMB/Ch/Bi 170 abc
Biochemistry and Biophysics of Macromolecules and Molecular Assemblies
9 units (3-1-5)
|
first, second, third terms
Prerequisites: Bi/Ch 110.
First term: detailed analysis of the structures of the four classes of biological molecules and the forces that shape them. Introduction to molecular biological and visualization techniques. Second term: basic principles of modern biophysical and structural methods to interrogate macromolecules from the atomic to cellular levels, including X-ray crystallography, NMR spectroscopy, molecular dynamics, electron and light microscopy, AFM, single molecule techniques, and systems biological simulations. Third term: detailed analysis of specific macromolecular machines and systems that illustrate the principles and biophysical methods taught in the first two terms.
Instructors:
Clemons, Jensen, Shan, staff
ESE/Ge/Ch 171
Atmospheric Chemistry I
9 units (3-0-6)
|
third term
Prerequisites: Ch 1 or equivalent.
A detailed course about chemical transformation in Earth's atmosphere. Kinetics, spectroscopy, and thermodynamics of gas-phase chemistry of the stratosphere and troposphere; sources, sinks, and lifetimes of trace atmospheric species; stratospheric ozone chemistry; oxidation mechanisms in the troposphere.
Instructors:
Seinfeld, Wennberg
ESE/Ge/Ch 172
Atmospheric Chemistry II
3 units (3-0-0)
|
first term
Prerequisites: ESE/Ge/Ch 171 or equivalent.
A lecture and discussion course about active research in atmospheric chemistry. Potential topics include halogen chemistry of the stratosphere and troposphere; aerosol formation in remote environments; coupling of dynamics and photochemistry; development and use of modern remote-sensing and in situ instrumentation. Graded pass/fail. Not offered 2011-12.
ESE/Ch/Ge 175
Environmental Organic Chemistry
9 units (3-0-6)
|
second term
A detailed analysis of the important chemical reactions and physicochemical processes governing the behavior and fate of organic compounds in the surface and subsurface aquatic environments. The course is focused on physical organic chemistry relevant to natural waters. Fundamental aspects of thermodynamics, kinetics, mechanisms, and transport are stressed.
Instructor:
Hoffmann
BMB/Ch 178
Enzyme Kinetics and Mechanisms
9 units (3-0-6)
|
first term
Prerequisites: Bi/Ch 110 a or equivalent.
Discussion of the energetic principles and molecular mechanisms that underlie enzymes' enormous catalytic proficiency and exquisite specificity. Practical kinetics sections discuss how to infer molecular mechanisms from rate/equilibrium measurements and their application to more complex biological systems, and include steady-state and pre-steady-state kinetics, and kinetics at the single molecule level.
Instructor:
Shan
Ch 180
Chemical Research
Units by arrangement
Offered to M.S. candidates in chemistry. Graded pass/fail.
BMB/Ch 202 abc
Biochemistry Seminar Course
1 unit
|
first, second, third terms
A course that includes a seminar on selected topics from outside faculty on recent advances in biochemistry. Students will participate in the seminar along with a formal discussion section with visiting faculty.
Instructor:
Clemons
Ch 212
Bioinorganic Chemistry
9 units (3-0-6)
|
third term
Prerequisites: Ch 112 and Bi/Ch 110 or equivalent.
Current topics in bioinorganic chemistry will be discussed, including metal storage and regulation, metalloenzyme structure and reactions, biological electron transfer, metalloprotein design, and metal-nucleic acid interactions and reactions.
Instructors:
Agapie, Winkler
Ch 213 abc
Advanced Ligand Field Theory
12 units (1-0-11)
|
first, second, third terms
Prerequisites: Ch 21 abc or concurrent registration.
A tutorial course of problem solving in the more advanced aspects of ligand field theory. Recommended only for students interested in detailed theoretical work in the inorganic field.
Instructors:
Gray, staff
Ch 224
Advanced Topics in Magnetic Resonance
9 units (2-0-7)
|
third term
Prerequisites: Ch 125 abc or Ph 125 abc or concurrent registration or equivalent; Ch 122 b or equivalent.
A detailed presentation of some of the important concepts in magnetic resonance unified by the spin density operator formalism. Topics will include both classic phenomena and recent development, especially in solid-state and two-dimensional NMR. Not offered 2011-12.
Ch 227 ab
Advanced Topics in Chemical Physics
9 units (3-0-6)
|
part a second term
Prerequisites: Ch 125 abc or Ph 125 abc or equivalent.
The general quantum mechanical theory of molecular collisions will be presented in detail. Quasi-classical, semi-classical, and other approximations. Applications to inelastic and reactive molecule-molecule and inelastic electron-molecule collisions. Not offered 2011-12.
Ch 228
Dynamics and Complexity in Physical and Life Sciences
9 units (3-0-6)
|
third term
This course is concerned with the dynamics of molecular systems, with particular focus on complexity, the elementary motions that lead to functions in chemical and biological assemblies. It will address principles of dynamics as they relate to the nature of the chemical bond. An overview of modern techniques, such as those involving lasers, NMR, and diffraction, for unraveling dynamics in complex systems. Applications from areas of physics, chemistry, and biology-from coherence and chaos to molecular recognition and self-assembly.
Instructor:
Zewail
Ch/Bi 231
Advanced Topics in Biochemistry
6 units (2-0-4)
|
third term
Transcriptional regulation in eukaryotes. Topics: the subunit structure of eukaryotic RNA polymerases and their role in transcriptional reactions; the composition of eukaryotic promoters, including regulatory units; general and specific transcription factors; developmental regulatory circuits and factors; structural motifs involved in DNA binding and transcriptional initiation and control.
Instructors:
Parker, Campbell
Ch 242 ab
Chemical Synthesis
9 units (3-0-6)
|
first, second terms
Prerequisites: Ch 41 abc.
An integrated approach to synthetic problem solving featuring an extensive review of modern synthetic reactions with concurrent development of strategies for synthesis design. Part a will focus on the application of modern methods of stereocontrol in the construction of stereochemically complex acyclic systems. Part b will focus on strategies and reactions for the synthesis of cyclic systems. Part a only offered first term. Part b will not be offered second term
Instructor:
Reisman
Ch 247
Organic Reaction Mechanisms
9 units (3-0-6)
|
second term
Prerequisites: Ch 41 abc, Ch 242 a recommended.
This course will discuss and uncover useful strategies and tactics for approaching complex reaction mechanisms prevalent in organic reactions. Topics include: cycloaddition chemistry, rearrangements, radical reactions, metal-catalyzed processes, photochemical reactions among others. Recommended only for students interested in advanced study in organic chemistry or related fields.
Instructor:
Stoltz
Ch 250
Advanced Topics in Chemistry
Units and term to be arranged
Content will vary from year to year; topics are chosen according to interests of students and staff. Visiting faculty may present portions of this course. Not offered 2011-12.
Ch 280
Chemical Research
Hours and units by arrangement
By arrangement with members of the faculty, properly qualified graduate students are directed in research in chemistry.
Published Date:
July 28, 2022